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Let-7 regulates cardiomyocyte regeneration

  
@article{SCI8711,
	author = {Yi-Fan Xu and Wei-Qun Ding},
	title = {Let-7 regulates cardiomyocyte regeneration},
	journal = {Stem Cell Investigation},
	volume = {2},
	number = {12},
	year = {2015},
	keywords = {},
	abstract = {In May of 2015, Kuppusamy et al. described a microRNA (miRNA)-driving maturation process in stem cell-derived cardiomyocytes (CMs) (1). This process elucidated the metabolism shifting through down-regulation of the phosphoinositide 3 kinase (PI3K)/AKT protein kinase/insulin pathway to an up-regulation of fatty acid metabolism, and provided a foundation for potential heart regeneration therapy using human embryonic stem cell-derived cardiomyocytes (hESC-CMs).},
	issn = {2313-0792},	url = {https://sci.amegroups.org/article/view/8711}
}