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CD34+ therapy-related acute promyelocytic leukemia in a patient previously treated for breast cancer

   
@article{SCI9482,
	author = {John Savooji and Fouzia Shakil and Humayun Islam and Delong Liu and Karen Seiter},
	title = {CD34+ therapy-related acute promyelocytic leukemia in a patient previously treated for breast cancer},
	journal = {Stem Cell Investigation},
	volume = {3},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Therapy-related acute myeloid leukemia (AML) is a long term complication of chemotherapy for a variety of cancers. In most cases, the marrow demonstrates high risk cytogenetics and the prognosis is poor. In a minority of patients “good risk” cytogenetics, including t(15;17)(q22;q12), are seen and the patient’s prognosis is similar to those who have de novo disease. Currently we present a patient who developed therapy-related acute promyelocytic leukemia (APL) after chemoradiotherapy for breast cancer. This case was especially atypical because the leukemic cells were CD34+, which is an unusual immunophenotype for APL. Recognition that this patient had APL, rather than the more common therapy-related MDS or AML, was imperative to initiate chemotherapy in a timely manner.},
	issn = {2313-0792},	url = {https://sci.amegroups.org/article/view/9482}
}