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Acute promyelocytic leukemia co-existing with JAK2 V617F positive myeloproliferative neoplasm: a case report

   
@article{SCI9625,
	author = {Aleksandra Mamorska-Dyga and Jingjing Wu and Pallavi Khattar and Faisal M. H. Ronny and Humayun Islam and Karen Seiter and Delong Liu},
	title = {Acute promyelocytic leukemia co-existing with JAK2 V617F positive myeloproliferative neoplasm: a case report},
	journal = {Stem Cell Investigation},
	volume = {3},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {The V617F mutation of Janus-associated kinase 2 (JAK2) is commonly seen in myeloproliferative neoplasms (MPN). Transformation of JAK2 positive MPNs to acute leukemia has been reported. We here report a case of acute promyelocytic leukemia which was later confirmed to have a co-existing JAK2 V617F positive MPN. In addition, the patient was found to have FLT3-TKD mutation, which, together with PML/RARa, could play a role in the MPN transformation to APL.},
	issn = {2313-0792},	url = {https://sci.amegroups.org/article/view/9625}
}