Role of adventitial MSC-like cells in chronic kidney disease

Cardiovascular diseases are the principal cause of death in the industrialized countries. Vascular wall calcification occurring in the late stages of cardiovascular diseases is an independent risk factor in patients with chronic kidney disease (CKD) (1,2). This process of arterial calcification in CKD may affect different arterial layers: the intima in association with atherosclerosis, and the media mostly in association with reduced kidney function (3).