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Stem Cell Investigation will cease publication in November 2023

Stem Cell Investigation is now archived and no longer receiving submissions with this publisher. All articles published in the journal during its time with AME Publishing Company will remain fully searchable through our websites.

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Original Article

Interplay between BMP2 and Notch signaling in endothelial-mesenchymal transition: implications for cardiac fibrosis

Pavel Docshin, Ahmad Bairqdar, Anna Malashicheva

Stem Cell Investigation

2023;

10:

(28 September 2023)

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Letter to the Editor

Primary central nervous system lymphoma: treatment access and outcomes in HIV positive patients in a minority rich cohort

Hiba Narvel, Charan Vegivinti, Sindhu Vikash, Abdul Hamid Bazarbachi, Kith Pradhan, Shuai Wang, M. Bakri Hammami, Nida Narvel, Shreyas Yakkali, Shehbaz Ansari, Adnan Gulam Nabi, Turab Mohammed, Ioannis Mantzaris, Marina Konopleva, Mendel Goldfinger, Kira Gritsman, Dennis Cooper, Aditi Shastri, Nishi Shah, Noah Kornblum, Amit Verma, R. Alejandro Sica

Stem Cell Investigation

2023;

10:

(24 August 2023)

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Original Article

Novel Human Umbilical Di-Chimeric (HUDC) cell therapy for transplantation without life-long immunosuppression

Maria Siemionow, Joanna Cwykiel, Lucile Chambily, Stephanie Gacek, Sonia Brodowska

Stem Cell Investigation

2023;

10:

(14 August 2023)

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Review Article

The quest for the holy grail: overcoming challenges in expanding human hematopoietic stem cells for clinical use

Sepideh Bastani, Frank J. T. Staal, Kirsten Canté-Barrett

Stem Cell Investigation

2023;

10:

(11 July 2023)

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Review Article

Identification and characterization of enhancer elements controlling cell type-specific and signalling dependent chromatin programming during hematopoietic development

Alexander Maytum, Ben Edginton-White, Constanze Bonifer

Stem Cell Investigation

2023;

10:

(25 June 2023)

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Letter to the Editor

Immunophenotypic analysis of human adipose-derived stem cells through multi-color flow cytometry

Paolo Giuseppe Limoli, Marcella Nebbioso

Stem Cell Investigation

2023;

10:

(09 June 2023)

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Original Article

Femur bone marrow from brain death deceased donors as source of human mesenchymal stromal cells for cell therapy

Lourdes Echarte, Alexandra Sujanov, Daniel Machin, Natalia Marquisá, Cristina Touriño

Stem Cell Investigation

2023;

10:

(23 May 2023)

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Case Report

Malignant clonal evolution from high proportion of monocytes in patients with aplastic anemia: a case report

Qiuhao Fu, Lingling Liu, Yingmei Li

Stem Cell Investigation

2023;

10:

(15 May 2023)

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Original Article

Transcriptomic analysis of feeder-free culture system for maintaining naïve-state pluripotency in human pluripotent stem cells

Wataru Isono, Tomoyuki Kawasaki, Justin K. Ichida, Kazunori Nagasaka, Osamu Hiraike, Akihiro Umezawa, Hidenori Akutsu

Stem Cell Investigation

2023;

10:

(19 April 2023)

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Review Article

Macrophages and stem/progenitor cells interplay in adipose tissue and skeletal muscle: a review

Malgorzata Kloc, Ahmed Uosef, Henry V. Ubelaker, Jacek Z. Kubiak, Rafik M. Ghobrial

Stem Cell Investigation

2023;

10:

(13 April 2023)

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Letter to the Editor

Immune reconstitution profile after allogeneic hematopoietic stem cell transplantation with post-transplant cyclophosphamide

Manuel Espinoza-Gutarra, Ayman Saad, Omer Jamy

Stem Cell Investigation

2023;

10:

(10 April 2023)

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Original Article

Neurogenic marker expression in differentiating human adipose derived adult mesenchymal stem cells

Neus Gomila Pelegri, Bruce K. Milthorpe, Catherine A. Gorrie, Jerran Santos

Stem Cell Investigation

2023;

10:

(23 March 2023)

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Review Article

Current status and prospects of regenerative medicine for spinal cord injury using human induced pluripotent stem cells: a review

Mitsuhiro Inoue, Ryo Yamaguchi, Ching Chi Jimmy He, Atsushi Ikeda, Hideyuki Okano, Jun Kohyama

Stem Cell Investigation

2023;

10:

(10 March 2023)

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Editorial Commentary

Recreating heterogeneity of bladder cancer microenvironment to study its recurrences and progression

François Bordeleau, David Brownell, Stephane Chabaud, Marc-Etienne Huot, Stephane Bolduc

Stem Cell Investigation

2023;

10:

(07 March 2023)

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Review Article

The role of macrophages in fracture healing: a narrative review of the recent updates and therapeutic perspectives

Bianca Braga Frade, Rhayra Braga Dias, Sara Gemini Piperni, Danielle Cabral Bonfim

Stem Cell Investigation

2023;

10:

(08 February 2023)

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Methodology

Optimization of adeno-associated virus (AAV) gene delivery into human bone marrow stem cells (hBMSCs)

Shaomian Yao, Weiqiong Rong, Yuanying Yuan

Stem Cell Investigation

2023;

10:

(02 February 2023)

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Original Article

Exosome-based cancer vaccine for prevention of lung cancer

Shuhan Meng, Aaron G. Whitt, Bryce F. Stamp, John W. Eaton, Chi Li, Kavitha Yaddanapudi

Stem Cell Investigation

2023;

10:

(09 January 2023)

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Editorial Commentary

A selective type of autophagy to maintain glioma stem cell activity

Khushbu Patel, Esperanza Arias

Stem Cell Investigation

2023;

10:

(06 January 2023)

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Original Article

Creation of human hematopoietic chimeric cell (HHCC) line as a novel strategy for tolerance induction in transplantation

Maria Siemionow, Sonia Brodowska, Klaudia Różczka, Claire Roesler

Stem Cell Investigation

2022;

(19 December 2022)

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Review Article

Leukemic stem cells and advances in hematopoietic stem cell transplantation for acute myeloid leukemia: a narrative review of clinical trials

Vikram Sumbly, Ian Landry, Christina Sneed, Qamar Iqbal, Anu Verma, Tenzin Dhokhar, Adeel Masood, Akshay Amaraneni

Stem Cell Investigation

2022;

(05 December 2022)

PDF Full Text (4302) Reporting Checklist COI Form Open Access

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Review Article

Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiation

Tianyu Guo, Xuejun Wang, Yigong Qu, Yu Yin, Tao Jing, Qing Zhang

Published online: 14 February 2015

PDF Full Text (26485) Open Access

Review Article

Cancer stem cells: progress and challenges in lung cancer

Amanda K. Templeton, Shinya Miyamoto, Anish Babu, Anupama Munshi, Rajagopal Ramesh

Published online: 15 April 2014

PDF Full Text (25059) Open Access

Review Article

TNF-α, a good or bad factor in hematological diseases?

Tian Tian, Min Wang, Daoxin Ma

Published online: 01 June 2014

PDF Full Text (22289) Open Access

Review Article

Evaluation of TCR repertoire diversity in patients after hematopoietic stem cell transplantation

Yangqiu Li, Ling Xu

Published online: 28 September 2015

PDF Full Text (20439) Open Access

Original Article

Stem cells from human hair follicles: first mechanical isolation for immediate autologous clinical use in androgenetic alopecia and hair loss

Pietro Gentile, Maria G. Scioli, Alessandra Bielli, Augusto Orlandi, Valerio Cervelli

Published online: 27 June 2017

PDF Full Text (16558) Open Access

Review Article

Regulatory factors of induced pluripotency: current status

Wei Zhao, Bo Ning, Chen Qian

Published online: 22 July 2014

PDF Full Text (15966) Open Access

Review Article

Current state of stem cell-based therapies: an overview

Riham Mohamed Aly

Published online: 15 May 2020

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Review Article

Recent advances and novel agents for FLT3 mutated AML

Rahul Pawar, Omar Preet Singh Bali, Bharat Kumar Malhotra, Gurpreet Lamba

Published online: 20 March 2014

PDF Full Text (14504) Open Access

Case Report

Cutaneous metastasis as an initial presentation of lung adenocarcinoma with KRAS mutation: a case report and literature review

Huijuan Liao, Shenhong Wu, Stephen R. Karbowitz, Nora Morgenstern, David R. Rose

Published online: 05 March 2014

PDF Full Text (13929) Open Access

Review Article

The role of mesenchymal stem/progenitor cells in sarcoma: update and dispute

Jilong Yang, Zhiwu Ren, Xiaoling Du, Mengze Hao, Wenya Zhou

Published online: 27 October 2014

PDF Full Text (13946) Open Access

Review Article

Reactive oxygen species in eradicating acute myeloid leukemic stem cells

Hui Zhang, Hai Fang, Kankan Wang

Published online: 07 June 2014

PDF Full Text (13176) Open Access

Review Article

Tyrosine kinase inhibitors targeting FLT3 in the treatment of acute myeloid leukemia

Yun Chen, Yihang Pan, Yao Guo, Wanke Zhao, Wanting Tina Ho, Jianlong Wang, Mingjiang Xu, Feng-Chun Yang, Zhizhuang Joe Zhao

Published online: 02 June 2017

PDF Full Text (12938) Open Access

Original Article

Reverse transcriptase and intron number evolution

Kemin Zhou, Alan Kuo, Igor V. Grigoriev

Published online: 28 September 2014

PDF Full Text (12576) Open Access

Review Article

Extracellular vesicles and aging

Paul D. Robbins

Published online: 19 December 2017

PDF Full Text (12016) Open Access

Review Article

Bone marrow fibrosis in primary myelofibrosis: pathogenic mechanisms and the role of TGF-β

Archana Agarwal, Kerry Morrone, Matthias Bartenstein, Zhizhuang Joe Zhao, Amit Verma, Swati Goel

Published online: 26 February 2016

PDF Full Text (12085) Open Access

Review Article

Calreticulin (CALR) mutation in myeloproliferative neoplasms (MPNs)

Wenyi Luo, Zhongxin Yu

Published online: 31 August 2015

PDF Full Text (11912) Open Access

Review Article

Interplay of retinal determination gene network with TGF-β signaling pathway in epithelial-mesenchymal transition

Yu Liu, Deguang Kong, Hua Wu, Xun Yuan, Hanxiao Xu, Cuntai Zhang, Gaosong Wu, Kongming Wu

Published online: 09 June 2015

PDF Full Text (11491) Open Access

Review Article

Cancer stem cells as a potential therapeutic target in breast cancer

Mingzhi Zhang, Zhaoming Li, Xudong Zhang, Yu Chang

Published online: 16 July 2014

PDF Full Text (11135) Open Access

Original Article

Stem Cell Ophthalmology Treatment Study: bone marrow derived stem cells in the treatment of non-arteritic ischemic optic neuropathy (NAION)

Jeffrey N. Weiss, Steven Levy, Susan C. Benes

Published online: 23 November 2017

PDF Full Text (11092) Open Access

Review Article

Clinical relevance between CALR mutation and myeloproliferative neoplasms

Zhiyuan Wu, Chen Zhang, Xiaochao Ma, Ming Guan

Published online: 16 February 2015

PDF Full Text (10841) Open Access

Full Most Read article list >>

Review Article

TNF-α, a good or bad factor in hematological diseases?

Tian Tian, Min Wang, Daoxin Ma

Review Article

Reactive oxygen species in eradicating acute myeloid leukemic stem cells

Hui Zhang, Hai Fang, Kankan Wang

Review Article

Cancer stem cells as a potential therapeutic target in breast cancer

Mingzhi Zhang, Zhaoming Li, Xudong Zhang, Yu Chang

Review Article

MicroRNAs as biomarkers in leukemia

Xinxin Wang, Baohua Zhu, Zunnan Huang, Liyong Chen, Zhiwei He, Hua Zhang

Review Article

The role of mesenchymal stem/progenitor cells in sarcoma: update and dispute

Jilong Yang, Zhiwu Ren, Xiaoling Du, Mengze Hao, Wenya Zhou

Review Article

Targeting cancer stem cells with oncolytic virus

Yin Tong, Wenbin Qian

Review Article

Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiation

Tianyu Guo, Xuejun Wang, Yigong Qu, Yu Yin, Tao Jing, Qing Zhang

Review Article

Cancer stem cells and exosome signaling

Bethany N. Hannafon, Wei-Qun Ding

Review Article

Interplay of retinal determination gene network with TGF-β signaling pathway in epithelial-mesenchymal transition

Yu Liu, Deguang Kong, Hua Wu, Xun Yuan, Hanxiao Xu, Cuntai Zhang, Gaosong Wu, Kongming Wu

Review Article

Expression and function of P2 receptors in hematopoietic stem and progenitor cells

Wenli Feng, Lina Wang, Guoguang Zheng

Review Article

Current insights into the diagnosis and treatment of inherited bone marrow failure syndromes in China

Xiaofan Zhu

Research Highlights

Shp2 regulates leukemic stem cell frequency in MLL-rearranged acute myeloid leukemia

Jie Wu

Editorial

Stem nourished by branches: glioblastomas co-opt classic neurotrophic factor signaling to maintain stem-like cell pool

Rukayat Taiwo, Tatenda Mahlokozera, Albert H. Kim

Editorial

Evolutionarily diverse mechanisms of germline specification among mammals: what about us?

Shino Mitsunaga, Toshi Shioda

Editorial

Epigenomic and single-cell profiling of human spermatogonial stem cells

Akihiko Sakashita, Yu-Han V. Yeh, Satoshi H. Namekawa, Shau-Ping Lin

Editorial

The puzzling mechanism of compensatory lung growth

Steven J. Mentzer

Editorial

Vaccination with induced pluripotent stem cells confers protection against cancer

Kavitha Yaddanapudi, Chi Li, John W. Eaton

Commentary

Megakaryocytes regulate the quiescence of hematopoietic stem cells through PF4: 2013 ASH meeting highlights

Yamei Chen, Delong Liu

Case Report

Isolated factor V deficiency in a patient with elevated PT and aPTT during routine pre-operative laboratory screening

Keyur Thakar, Kaushal Parikh, Yamei Chen, Delong Liu

Original Article

Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells

Gay Carter, Rekha Patel, André Apostolatos, Michel Murr, Denise R. Cooper, Niketa A. Patel

Original Article

Reverse transcriptase and intron number evolution

Kemin Zhou, Alan Kuo, Igor V. Grigoriev

Original Article

Interleukin 8/KC enhances G-CSF induced hematopoietic stem/ progenitor cell mobilization in Fancg deficient mice

Yan Li, Wen Xing, Yong-Zheng He, Shi Chen, Steven D. Rhodes, Jin Yuan, Yuan Zhou, Jun Shi, Jie Bai, Feng-Kui Zhang, Wei-Ping Yuan, Tao Cheng, Ming-Jiang Xu, Feng-Chun Yang

Original Article

Quantitative analyses of myelofibrosis by determining hydroxyproline

Wanke Zhao, Wan-Ting Tina Ho, Zhizhuang Joe Zhao

Journal Highlight more

Stem Cell Investigation is an international, open access, peer-reviewed, PubMed-indexed online journal covering basic, translational, and clinical research on all aspects of stem cells, e.g. embryonic stem cells, induced pluripotent stem cells, adult tissue-specific stem/progenitor cells, cancer stem like cells, stem cell niche, stem cell technology, stem cell based drug discovery, and regenerative medicine.